4DWheat: diversity, domestication, discovery, delivery


Funding period: 2019-2023
Lead: Sylvie Cloutier
Total GRDI funding: $2,805,423

Wheat (Triticum spp.) is the most important crop for current and future global food security. Canada is a major supplier of wheat globally, and supports a Canadian agri-food industry of >$6 billion annually. Wheat improvement programs across the country are working to develop new wheat cultivars that can tolerate our hot and dry environments, are resilient to often erratic weather extremes, and are resistant to emerging diseases. 4DWheat will apply the very latest in genomic strategies to focus on two major challenges: enhancing yield and managing producer risk to important diseases. One strategy is to utilize genetic diversity lost from breeding since wheat was domesticated more than 10,000 years ago to fully capture diversity in wheat breeding.


  • Fatima F, McCallum BD, Pozniak CJ, Hiebert C, McCartney C, Fedak G, You FM, Cloutier S. 2020. Identification of new leaf rust resistance loci in wheat and wild relatives by array-based SNP genotyping and association genetics. Frontiers Plant Sci 16(11):583738. https://doi.org/10.3389/fpls.2020.583738
  • Sharma JS, McCallum BD, Hiebert CW. 2022. Development of single nucleotide polymorphism-based functional molecular markers from the Lr22a gene sequence in wheat (Triticum aestivum). Plant Breeding 141:204-211. https://doi.org/10.1111/pbr.13007
  • Walkowiak S, Gao L, Monat C, Haberer G, Kassa MT, Brinton J, Ramirez-Gonzalez RH, Kolodziej MC, Delorean E, Thambugala D, Klymiuk V, Byrns B, Gundlach H, Bandi V, Siri JN, Nilsen K, Aquino C, Himmelbach A, Copetti D, Ban T, Venturini L, Bevan M, Clavijo B, Koo DH, Ens J, Wiebe K, N'Diaye A, Fritz AK, Gutwin C, Fiebig A, Fosker C, Fu BX, Accinelli GG, Gardner KA, Fradgley N, Gutierrez-Gonzalez J, Halstead-Nussloch G, Hatakeyama M, Koh CS, Deek J, Costamagna AC, Fobert P, Heavens D, Kanamori H, Kawaura K, Kobayashi F, Krasileva K, Kuo T, McKenzie N, Murata K, Nabeka Y, Paape T, Padmarasu S, Percival-Alwyn L, Kagale S, Scholz U, Sese J, Juliana P, Singh R, Shimizu-Inatsugi R, Swarbreck D, Cockram J, Budak H, Tameshige T, Tanaka T, Tsuji H, Wright J, Wu J, Steuernagel B, Small I, Cloutier S, Keeble-Gagnère G, Muehlbauer G, Tibbets J, Nasuda S, Melonek J, Hucl PJ, Sharpe AG, Clark M, Legg E, Bharti A, Langridge P, Hall A, Uauy C, Mascher M, Krattinger SG, Handa H, Shimizu KK, Distelfeld A, Chalmers K, Keller B, Mayer KFX, Poland J, Stein N, McCartney CA, Spannagl M, Wicker T, Pozniak CJ. 2020. Multiple wheat genomes reveal global variation in modern breeding. Nature 588(7837):277-283. http://dx.doi.org/10.1038/s41586-020-2961-x
  • Wang L, Zhu T, Rodriguez JC, Deal KR, Dubcovsky J, McGuire PE, Lux T, Spannagl M, Mayer KFX, Baldrich P, Meyers BC, Huo N, Gu YQ, Zhou H, Devos KM, Bennetzen JL, Unver T, Budak H, Gulick PJ, Galiba G, Kalapos B, Nelson DR, Li P, You FM, Luo MC, Dvorak J. 2021. Aegilops tauschii genome assembly Aet v5.0 features greater sequence contiguity and improved annotation. G3 (Bethesda), Dec8; 11(12):jkab325. https://doi.org/10.1093/g3journal/jkab325

Contact us

For additional information, please contact:
Genomics R&D Initiative
Email: info@grdi-irdg.collaboration.gc.ca