Funding period: 2019-2023
Lead: Jim Strong
Total GRDI funding: $400,000
Ebola virus is an example of a high consequence pathogen, being highly contagious and having high mortality rates, with no licensed vaccines or treatments available. It is of utmost importance to quickly diagnose such pathogens in order to administer appropriate patient care and isolation. The development of CRISPR-based diagnostics can provide results in a timely manner and fill this gap. Implementation of CRISPR-based diagnostics will expand response options against high consequence pathogens and will address the need for faster, cheaper, and more robust diagnostics for emerging infectious diseases of public health concern.
Publication
- Li H, Bello A, Smith G, Kielich DMS, Strong JE, and Pickering BS. 2022. Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus. PLOS Neg Trop Dis, Mar 10. https://doi.org/10.1371/journal.pntd.0010285
Contact us
For additional information, please contact:
Genomics R&D Initiative
Email: info@grdi-irdg.collaboration.gc.ca