Funding period: 2020-2024
Lead: Francois Gagné
Total GRDI funding: $120,000
Development of qPCR approach to detect genomic damage and elucidate DNA repair activities in mussels and hydra (invertebrates). The hydra is becoming an interesting model for environmental risk assessment given its high sensitivity compared to the other usual organisms such as Daphnia magna and freshwater mussels (unionidae).
Publications
- André C, Auclair J, Gagné F. 2024. The influence of rainfall events on the toxicity of urban wastewaters to freshwater mussels Elliptio complanata. Comp Biochem Physiol 277: 109842. https://doi.org/10.1016/j.cbpc.2024.109842
- André C, Duy SV, Sauvé S and F., Gagné 2023 Comparative toxicity of urban wastewaters and rainfall overflows in caged freshwater mussels Elliptio complanata. Front Physiol 14: 12336569. https://doi.org/10.3389/fphys.2023.1233659
- André C, Gagné F. The comparative toxicity of rainfall overflows and a municipal effluent plume in Elliptio complanate using a novel qPCR array approach. 2020. Comp Biochem Physiol C Toxicol Pharmacol. 232:108760. https://doi.org/10.1016/j.cbpc.2020.108760
- Hanana H, Kleinert C, Gagné F. 2021. Toxicity of representative mixture of five rare earth elements in juvenile rainbow trout (Oncorhynchus mykiss). Environ Sci Pollut Res Int. 28: 28263-28274. https://doi.org/10.1007/s11356-020-12218-5
- Hanana H, Taranu ZE, Turcotte P, Gagnon C, Kowalczyk J, Gagné F. Evaluation of general stress, detoxification pathways, and genotoxicity in rainbow trout exposed to rare earth elements dysprosium and lutetium.2021. Ecotoxicol Environ Saf. 208:111588. https://doi.org/10.1016/j.ecoenv.2020.111588
Contact us
For additional information, please contact:
Genomics R&D Initiative
Email: info@grdi-irdg.collaboration.gc.ca