Single nucleotide variant subtyping of Salmonella Enteritidis and Salmonella Heidelberg


Funding period: 2014-2019
Lead: Roger Johnson
Total GRDI funding: $452,534

Salmonellosis is a very common foodborne illness, with Salmonella serovars Enteritidis (SE) and Heidelberg (SH) among the most frequent causes in Canada. Reliable subtyping methods are required for outbreak detection, tracking, and source attribution. Current subtyping methods, including the gold standard (Pulsed Field Gel Electrophoresis) lack the high resolution needed to accurately subtype these two highly clonal serovars. This project aims to develop and validate a simple Single Nucleotide Variants analysis platform for end users in public health laboratories. Importantly, the identified variants for both serovars can be integrated into future analysis of whole-genome sequences, enhancing federal and provincial public health responses to SE and SH infections.

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For additional information, please contact:
Genomics R&D Initiative