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Government of Canada researchers are unravelling a mystery that scientists around the world have been working on since the 1940s—understanding the genetic mechanisms that enable genes, including AMR genes—to move from one species of bacteria to another, a key element in understanding how AMR is transmitted.
Funding from the federal Genomics Research and Development Initiative Antimicrobial Resistance project (GRDI‑AMR) has enabled researchers at the PHAC to assemble genetic data from thousands of bacterial isolates, as well as the bioinformatics tools needed to use the data to advance AMR research—including how and where antimicrobial resistance (AMR) can circulate among human, food production and the environment.
GRDI funding has enabled researchers at the Canadian Food Inspection Agency (CFIA) to routinely identify antimicrobial resistance (AMR) genes in their genetic analysis of pathogenic bacteria such as disease-causing types of E. coli and Salmonella.
New research into antimicrobial resistance (AMR) funded through the Government of Canada's Genomics Research and Development Initiative (GRDI) shows it may be possible to eliminate the preventive use of antibiotics in Canada's poultry industry.
With funding from the GRDI, some two dozen federal scientists from 5 departments and agencies are collaborating in a major, 5-year research project in support of Canada's national action plan to address the growing threat of antimicrobial resistance (AMR).
Researchers working on the Food and Water Safety project funded by the Genomics R&D Initiative developed the bioinformatics capacity needed to ensure Canadians enjoy the full potential of genomics to enhance the safety of Canada's food supply.
The Genomics R&D Initiative investment in the Food and Water Safety research project has returned extensive benefits to Canadians, enhancing what is already one of the most respected food safety systems in the world.
New knowledge and tools developed through the Food and Water Safety project funded by the Genomics R&D Initiative will enable Canada to better address some of the most serious threats to our food and water supply—E. coli and Salmonella Enteritidis—including the capacity to identify different strains of these bacteria quickly and with high confidence.
Among other achievements, the Food and Water Safety project funded by the Genomics R&D Initiative has provided a first-ever national perspective on where to find potentially deadly strains of E. coli in our environment.
With funding from the Genomics R&D Initiative, federal researchers have collaborated in reducing the time it takes to identify E. coli O157: H7 in food to as little as 20 minutes.